مقایسه شاخص های استرس اکسیداتیو بارداری با زایمان بی درد و ارتباط مقادیر زایمانی آنها در نوزاد

Abstract Background: Studies show stress was caused by labour can increase oxygen demand and may be involved in oxidative stress. So this study compared indicators of oxidative stress in pregnancy with labor and correlation labor indices with newborn. Methods: In this cross – sectional study in 1386, 60 pregnant women at 38-40 weeks gestation were sampled and drowned 5 cc blood. All of the mothers for blood sample was taken written consent form. After interring pain less labor through of Entonox method 5 cc of venous blood taken at the second stage of labor and newborn cord. Then lipid peroxidation, thiols groups and total antioxidant capacity was assessed. Result: findings showed that the mean age was 24.0862 ± 4.08. Lipid peroxidation in pregnancy was 4.61 ± 2.712 and during labour was 4.606 ± 3.32, that the difference was not significant (p=0.994). Thiol index in pregnancy was 0.284 ± .3889 and during lbour 0.2656 ± .24371 that difference was not significant (p= 0.694). There wasn’t any significant difference in FRAP levels in pregnancy 1.26 ± 1.015 and labour 1.370 ± 1.1126 too (p=0.56). Significant positive correlation between maternal and fetal index thiols (p=0.002) and lipid peroxidation was observed (p=0.001). Conclusion: The results showed that oxidative stress indicators in the labor does not differ with respect to pregnancy and can be used for this method of analgesia